{"title":"Digestive","description":"\u003cp class=\"rb-lede\"\u003eGarbage collection for the gut. Spore-forming probiotics that survive a strip format, plus the enzymes and prebiotic fibre that go with them.\u003c\/p\u003e","products":[{"product_id":"gc-digestive","title":"RUNTIME GC","description":"\u003cp class=\"rb-lede\"\u003eGarbage collection, on a schedule. A 10-billion-CFU spore-forming probiotic plus three proteolytic enzymes; the strain here was trialled at 6 billion CFU, and this strip carries more.\u003c\/p\u003e\n\u003cp class=\"rb-note\"\u003eBacillus coagulans is spore-forming, which is why it survives a strip format that would kill most probiotic strains.\u003c\/p\u003e\n\u003ch3\u003eSpec\u003c\/h3\u003e\n\u003ctable class=\"rb-spec\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eBacillus coagulans\u003c\/th\u003e\n\u003ctd\u003e10 Billion CFU (50 mg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDigestive Enzymatic Blend\u003c\/th\u003e\n\u003ctd\u003e40 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003e  Papain\u003c\/th\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003e  Bromelain\u003c\/th\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003e  Protease\u003c\/th\u003e\n\u003ctd\u003e10 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFormat\u003c\/th\u003e\n\u003ctd\u003e30 sublingual strips\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFlavour\u003c\/th\u003e\n\u003ctd\u003eMixed Berry\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch3\u003eProtocol\u003c\/h3\u003e\n\u003cp\u003eOne strip on the tongue, allow to dissolve. Maximum one strip per day.\u003c\/p\u003e\n\u003ch3\u003eSupports\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eSupports normal gut balance\u003c\/li\u003e\n\u003cli\u003eAids natural protein digestion\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eEvidence\u003c\/h3\u003e\n\u003cp class=\"rb-note\"\u003eGraded against what was actually tested. Where the trial dose differs from this strip, both numbers are shown.\u003c\/p\u003e\n\u003cdiv class=\"rb-evidence\"\u003e\n\u003cdiv class=\"rb-ev\" data-grade=\"Strong\"\u003e\n\u003cp class=\"rb-ev-head\"\u003e\u003cspan class=\"rb-grade\"\u003eStrong\u003c\/span\u003e\u003cspan class=\"rb-ev-active\"\u003eBacillus coagulans\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"rb-ev-finding\"\u003eCONSORT-compliant double-blind placebo-controlled trial, 40 IBS patients (Rome IV), 80 days. Statistically significant improvement across every measured GI symptom versus placebo, including bloating.\u003c\/p\u003e\n\u003cp class=\"rb-ev-dose\"\u003eStudied at 6 billion CFU\/day · This strip: 10 billion CFU\u003c\/p\u003e\n\u003cp class=\"rb-ev-src\"\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7837859\/\" target=\"_blank\" rel=\"nofollow noopener\"\u003eSource\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rb-ev\" data-grade=\"Preliminary\"\u003e\n\u003cp class=\"rb-ev-head\"\u003e\u003cspan class=\"rb-grade\"\u003ePreliminary\u003c\/span\u003e\u003cspan class=\"rb-ev-active\"\u003eBromelain\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"rb-ev-finding\"\u003eReview evidence establishes bromelain is absorbed intact and stays biologically active, breaking dietary protein into peptides and amino acids. The mechanism is well described; controlled digestion endpoints in healthy adults are not.\u003c\/p\u003e\n\u003cp class=\"rb-ev-dose\"\u003eStudied at n\/a (review) · This strip: 15 mg\u003c\/p\u003e\n\u003cp class=\"rb-ev-src\"\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11243481\/\" target=\"_blank\" rel=\"nofollow noopener\"\u003eSource\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rb-ev\" data-grade=\"Preliminary\"\u003e\n\u003cp class=\"rb-ev-head\"\u003e\u003cspan class=\"rb-grade\"\u003ePreliminary\u003c\/span\u003e\u003cspan class=\"rb-ev-active\"\u003eBromelain\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"rb-ev-finding\"\u003eMeta-analysis of 6 RCTs (312 patients) found significant pain reduction after third-molar surgery (SMD −0.49 at 24 h, p=0.003). Best available human data, but a post-surgical inflammation endpoint, not digestion.\u003c\/p\u003e\n\u003cp class=\"rb-ev-dose\"\u003eStudied at see source · This strip: 15 mg\u003c\/p\u003e\n\u003cp class=\"rb-ev-src\"\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6344017\/\" target=\"_blank\" rel=\"nofollow noopener\"\u003eSource\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3\u003eContents\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eOther ingredients:\u003c\/strong\u003e Pullulan, Mannitol, Monk Fruit Extract, Cellulose, Lecithin, Mixed Berry Flavor, Steviol Glycosides.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDietary:\u003c\/strong\u003e Gluten-free  ·  Vegetarian  ·  Lactose-free  ·  Allergen-free  ·  Hormone-free  ·  Antibiotic-free  ·  Alcohol-free  ·  Cruelty-free\u003c\/p\u003e\n\u003ch3\u003ePackaging\u003c\/h3\u003e\n\u003cp class=\"rb-note\"\u003eOnly the metal tin is branded. The individual strip packets inside ship with the manufacturer's generic label and cannot be customised.\u003c\/p\u003e\n\u003cp class=\"rb-fda\"\u003e\u003csmall\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/small\u003e\u003c\/p\u003e","brand":"RUNTIME","offers":[{"title":"30 strips","offer_id":62153860448626,"sku":"AAV9DGUT","price":35.9,"currency_code":"USD","in_stock":true}]},{"product_id":"probiotic-metabolism","title":"RUNTIME Probiotic","description":"\u003cp class=\"rb-lede\"\u003eA probiotic and the fibre that feeds it, in one strip. B. lactis at 10 billion CFU with polydextrose, so the pre- and probiotic ship together rather than as two SKUs.\u003c\/p\u003e\n\u003cp class=\"rb-note\"\u003eRead the polydextrose row before you buy this for the fibre. The dose here is a fraction of what the trials used.\u003c\/p\u003e\n\u003ch3\u003eSpec\u003c\/h3\u003e\n\u003ctable class=\"rb-spec\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eBifidobacterium lactis\u003c\/th\u003e\n\u003ctd\u003e10 Billion CFU (37.5 mg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePolydextrose (prebiotic fibre)\u003c\/th\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFormat\u003c\/th\u003e\n\u003ctd\u003e30 sublingual strips\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFlavour\u003c\/th\u003e\n\u003ctd\u003eMixed Berry\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch3\u003eProtocol\u003c\/h3\u003e\n\u003cp\u003eOne strip on the tongue, allow to dissolve. Maximum one strip per day.\u003c\/p\u003e\n\u003ch3\u003eSupports\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eSupports daily digestive wellness\u003c\/li\u003e\n\u003cli\u003eSupports a balanced gut environment\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eEvidence\u003c\/h3\u003e\n\u003cp class=\"rb-note\"\u003eGraded against what was actually tested. Where the trial dose differs from this strip, both numbers are shown.\u003c\/p\u003e\n\u003cdiv class=\"rb-evidence\"\u003e\n\u003cdiv class=\"rb-ev\" data-grade=\"Moderate\"\u003e\n\u003cp class=\"rb-ev-head\"\u003e\u003cspan class=\"rb-grade\"\u003eModerate\u003c\/span\u003e\u003cspan class=\"rb-ev-active\"\u003eBifidobacterium lactis\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"rb-ev-finding\"\u003e6-month randomised double-blind placebo-controlled trial, 56 young Type 1 Diabetes patients, probiotic including B. lactis AP-32 as an insulin adjunct. Significantly reduced fasting glucose and HbA1c. A clinical population, not healthy adults.\u003c\/p\u003e\n\u003cp class=\"rb-ev-dose\"\u003eStudied at see source · This strip: 10 billion CFU\u003c\/p\u003e\n\u003cp class=\"rb-ev-src\"\u003e\u003ca href=\"https:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2022.754401\/full\" target=\"_blank\" rel=\"nofollow noopener\"\u003eSource\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rb-ev\" data-grade=\"Preliminary\"\u003e\n\u003cp class=\"rb-ev-head\"\u003e\u003cspan class=\"rb-grade\"\u003ePreliminary\u003c\/span\u003e\u003cspan class=\"rb-ev-active\"\u003ePolydextrose\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"rb-ev-finding\"\u003eDose-dependent increases in Lactobacilli and Bifidobacteria, and raised butyrate and propionate production in fermentation studies. Prebiotic fibre trials run in grams per day; this strip carries 50 mg.\u003c\/p\u003e\n\u003cp class=\"rb-ev-dose\"\u003eStudied at grams\/day · This strip: 50 mg\u003c\/p\u003e\n\u003cp class=\"rb-ev-src\"\u003e\u003ca href=\"https:\/\/www.mdpi.com\/2072-6643\/5\/4\/1417\" target=\"_blank\" rel=\"nofollow noopener\"\u003eSource\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rb-ev\" data-grade=\"Moderate\"\u003e\n\u003cp class=\"rb-ev-head\"\u003e\u003cspan class=\"rb-grade\"\u003eModerate\u003c\/span\u003e\u003cspan class=\"rb-ev-active\"\u003ePolydextrose\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"rb-ev-finding\"\u003e4-week double-blind RCT, 250 adults with functional constipation. Polydextrose with oligosaccharides significantly improved stool consistency, comparable to psyllium and wheat bran.\u003c\/p\u003e\n\u003cp class=\"rb-ev-dose\"\u003eStudied at see source · This strip: 50 mg\u003c\/p\u003e\n\u003cp class=\"rb-ev-src\"\u003e\u003ca href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/19490976.2023.2197837\" target=\"_blank\" rel=\"nofollow noopener\"\u003eSource\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3\u003eContents\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eOther ingredients:\u003c\/strong\u003e Pullulan, Cellulose, Mannitol, Mixed Berry Flavor, Sunflower Lecithin, Monk Fruit Extract, Erythritol, MCT, Malic Acid, Steviol Glycoside.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDietary:\u003c\/strong\u003e Gluten-free  ·  Lactose-free  ·  Hormone-free  ·  All-natural  ·  Antibiotic-free  ·  Alcohol-free  ·  Cruelty-free\u003c\/p\u003e\n\u003ch3\u003ePackaging\u003c\/h3\u003e\n\u003cp class=\"rb-note\"\u003eOnly the metal tin is branded. The individual strip packets inside ship with the manufacturer's generic label and cannot be customised.\u003c\/p\u003e\n\u003cp class=\"rb-fda\"\u003e\u003csmall\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/small\u003e\u003c\/p\u003e","brand":"RUNTIME","offers":[{"title":"30 strips","offer_id":62153860612466,"sku":"AAV9PROB","price":39.0,"currency_code":"USD","in_stock":true}]}],"url":"https:\/\/runtimebio.com\/collections\/digestive.oembed","provider":"Runtime Bio","version":"1.0","type":"link"}